Clostridium Difficile (C. diff) Diagnosis

C. diff Diagnosis

Clostridium difficle diagnosis is done by obtaining stool specimen. Clostridium difficle produces Toxin A & B and it’s presence can be detected in stool sample. Three main types of lab tests prescribed are:

  1. Enzye immunoassay
  2. Polymerase chain reaction (PCR)
  3. Tissue culture assay

In order to ensure accurate results some hospitals use both Enzyme immunoassay and Tissue culture assay testing. This condition is also characterized by inflammation and pseudomembranes in the lower colon and Sigmoidoscopy is used to verify this.

Complicated stages of C. diff are symbolized by the thickening of the walls of the colon which is associated with pseudomembranous colitis.

PC: Medical Xpress